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Kansas State Collegian

Kansas State Collegian

The independent student news publication at Kansas State University

Kansas State Collegian

I Tested the 3 Best Supplements for Menopause Weight Gain: OTC Diet Pills for Women Over 50 


In my role as a health and wellness expert, I’ve spent many years helping women through the many changes menopause brings. One of the most common concerns is weight gain. Many women gain weight during their menopausal transitions. Unfortunately, it’s a common problem area that’s often overlooked during this important stage of women’s lives.

Addressing the problem of weight management during the change isn’t just a matter of improving physical appearance, it’s also about improving women’s overall health and well-being. Women often gain weight during menopause due to hormonal changes, specifically a decrease in estrogen, which can slow metabolism and lead to increased fat storage.

I have compiled a list of the best supplements for tackling menopause weight gain in 2024 that can be purchased online or over the counter. When used alongside a balanced diet, regular exercise, and healthy lifestyle practices, they can help take the sting out of the “female climacteric” by controlling or reversing the effect menopause has on body weight.

Recommended Supplements for Menopause Weight Gain 

All 3 brands can be purchased over the counter or online from the manufacturers’ websites. 

  1. PhenQ – Multi Action Fat Burner and Appetite Suppressant
  2. Yourbiology Gut+ – Female Probiotic for Menopause Weight Loss
  3. Capsiplex Trim – Thermogenic Fat Burner for Women

All 3 menopause supplements for weight loss can be used together for greater effect (separate purchases required)

Most Effective Supplements for Weight Gain During Menopause

Here are detailed reviews and ratings for the three brands.

#1. PhenQ

  • Cost: $69.99 per month
  • Best value: $41.99 per month (buy 3 bottles get 2 free)
  • Rating: 5/5 
  • Where to buy: PhenQ website

“In my opinion PhenQ is the best supplement for menopause weight gain. If you are experiencing menopausal symptoms PhenQ’s natural formula helps you burn excess fat and keep your hunger pangs at bay.”

PhenQ is a powerful diet pill that was developed to compete with Phentermine, a popular prescription-only weight loss tablet. It works well in that role and has also become the top choice among people who are seeking safe alternatives to other prescription weight loss drugs such as Ozempic, Wegovy and Mounjaro.

PhenQ has amassed more than 190,000 satisfied customers, many of whom record weight losses of 10-15 pounds per month. That’s very impressive for a weight loss pill that’s powered by plant extracts and other natural ingredients.

Much of PhenQ’s success is due to the choice of ingredients used in its formula. All of them have excellent scientific credentials in areas relating to weight loss and, acting in synergy, they provide a multi-pronged approach that other diet pills are unable to match.

Due to the strength of its formula and the positive feedback it has received in countless customer reviews, I rate PhenQ as the top choice for women who want to reverse menopausal weight gain and return to a healthy body weight.

PhenQ Benefits

PhenQ supports weight loss by:

  • Suppressing hunger and cravings
  • Boosting metabolism to support fat loss
  • Increasing energy levels to prevent fatigue
  • Enhancing mood to promote a positive state of mine
  • Inhibiting fat storage to prevent further weight gain

How to Use PhenQ

The dose is two tablets per day. You take the first one with breakfast and the second one with lunch.

Although the PhenQ formula contains ingredients that inhibit fat storage, it’s not a magic pill. As with other prescription weight loss drugs and OTC other brands of OTC diet pills, to get the best from PhenQ, you need to commit to a healthy lifestyle that includes a low-calorie diet and regular effort with exercise.

How PhenQ Works

As I already pointed out, PhenQ is a multi-functional weight loss pill. The first thing it does is suppress appetite and cravings. This makes it easier to stick to a calorie-controlled diet without having to contend with unpleasant hunger sensations or urges for high-calorie foods.

Helped by PhenQ, a low-calorie diet creates an energy shortage in the body. The body can’t function without energy so it starts breaking down its stores of fat to the extra energy it needs.

The next thing PhenQ does is boost metabolism. This increases calorie expenditure, increasing the energy shortage the body is experiencing, resulting in a greater need for fat burning.

When the body experiences an energy deficit, it can cause fatigue. This is unpleasant and can reduce daytime productivity. It can also make it more difficult to commit to regular exercise.

PhenQ compensates for this by providing energy-boosting ingredients, thereby removing another major weight loss hurdle that can bring extra misery to perimenopausal women’s lives.

The dietary restraints that are necessary for effective weight loss can negatively impact mood so PhenQ provides ingredients that fight depression and make it easier to maintain a positive state of mind.

The mood-enhancing abilities of PhenQ can be especially useful to women going through menopause because the changes that take place often cause problems in this area. Mood swings and poor mood affect around 4 in 10 menopausal women. I’m not comparing PhenQ’s abilities to those of prescription antidepressants but it does have the potential to provide a pretty good pick-me-up.

PhenQ Ingredient Highlights

The PhenQ formula is quite complex. It consists of 13 ingredients.

Here are a few of the key players:

  • Nopal: A cactus extract that’s high in fiber and has a long history of use as a hunger suppressant. Recent research shows nopal further supports weight loss by increasing metabolism and inhibiting the absorption of dietary fats.
  • Capsimax powder: A branded ingredient that provides capsicum extract. Research shows the capsaicin it contains supports weight loss by controlling hunger, boosting metabolism, aiding lipolysis (fat breakdown), and discouraging fat cell formation.
  • Chromium Picolinate: Chromium is a mineral that helps control blood sugar, preventing the spikes that cause sudden cravings for sugar or carbs. Although there are other chromium-providing ingredients, the picolinate form boasts superior bioavailability. The body finds it very easy to process and put to use.
  • Caffeine:  A popular stimulant, caffeine elevates the body’s energy levels and mental focus by influencing certain areas of the brain. Research shows caffeine also has value as a thermogenic fat burner and, to a lesser extent, as an appetite suppressant.
  • L-Carnitine: This amino acid invigorates the body by helping transport fatty acids from the blood into the mitochondria of cells. Data from clinical trials shows supplements that provide L-carnitine can also relieve depression and stabilize the mind to prevent mood swings. These abilities are due to the amino acid having a positive influence on neurotransmitter production.

If weight gain is one of the changes menopause has brought to your life, these and the other PhenQ ingredients can help you turn things around. The formula has already done this for countless women in the same situation and you have nothing to lose by giving it a go because the manufacturer provides a 60-day money-back guarantee.

You can order PhenQ directly from the official website. The official website is available in several language options and shipping is free.

#2. Yourbiology Gut+

  • Cost: $64.99
  • Best value: $38.99 per month (buy 3 bottles get 2 free)
  • Rating: 4/5
  • Where to buy: YourBiology website

Yourbiology Gut+ is a high-quality probiotic supplement specially formulated for women. It’s a great choice for women at all stages of their lives, including menopause.

As with all probiotic products, Yourbiology Gut+ provides the gut with daily top-ups of friendly gut bacteria, several of which have proven to be useful for treating typical menopause symptoms including hot flashes, night sweats, poor bone health, and menopause belly.

When you take probiotic supplements, the digestive enzymes in the stomach can kill some of the bacteria. This reduces the effectiveness. Although not all supplement manufacturers tackle this problem the company responsible for Yourbiology Gut+ is one of the few that has. Each capsule has a special coating that resists the harsh environment inside the stomach, safely transporting the bacteria to the gut.

The capsules also contain fructo-oligosaccharides (FOS) to help get the fresh bacteria colonies off to a good start. FOS is a high-quality prebiotic fiber that nourishes good bacteria so it can thrive.

As with all the top probiotic products, YourBiology Gut+ is shelf-stable. That means you don’t need to worry about the probiotics dying during transit or keep the supplement in your refrigerator.

Key Benefits of Yourbiology Gut+

Collectively, the probiotics in YourBiology Gut+ offer multiple benefits including helping to rectify or prevent menopause weight gain.

Some of the main benefits include:

  • Improved gut health
  • Reduced bloating
  • Balanced vaginal flora
  • Stress reduction
  • Glowing skin
  • Weight management support

How Youbiology Gut+ Works

Yourbiology Gut+ provides several strains of live probiotic bacteria.  Each dose provides 40 Billion Culture-Forming Units (CFU). That’s a generous dose but not excessively high.

The human gut is home to a variety of microorganisms including a diverse range of bacteria. Some of it is pathogenic, meaning it has the potential to cause illness. Probiotic bacteria is the “good” kind. It fights gut pathogens, helping to retain harmony in the gut. If levels drop, the harmful bacteria species gain the upper hand. This disruption in the normal microbial community is known as dysbiosis. It can cause a variety of health problems.

Probiotic supplements are popular because they help keep the gut healthy, resulting in a variety of knock-on benefits. However, certain probiotic bacteria species and strains offer help in very specific areas. Yourbiology Gut+ provides strains that have been specially chosen because they have scientifically proven value in areas relating to female health and well-being, including hormone regulation, and help to overcome menopausal weight gain.

YourBiology Gut+ Ingredient Highlights

The supplement provides probiotics from four bacteria families. Each one provides a diverse range of health benefits. However, not all of them are relevant to the theme of this article, so we will focus on the value they offer to menopausal women and, in particular, those who have gained weight due to the hormonal changes that take place due to menopause

  • Lactobacillus Acidophilus:  L. acidophilus ranks among the best probiotics for controlling the symptoms of menopause.  Research published in the Journal of Clinical Medicine (July 2020) shows supplements that provide L. acidophilus can relieve a variety of menopausal symptoms including fatigue, heart palpitations, hot flashes, vaginal dryness, and weight gain. Noting the probiotic’s efficacy and safety, the researchers pointed out its potential value as an alternative to hormone replacement therapy (HRT).
  • Lactobacillus Plantarum: Another probiotic that has associations with weight loss, L. plantarum offers a variety of benefits to menopausal women. One of the things it does is strengthen bones to help prevent osteoporosis.
  • Lactobacillus Paracasei: Research shows this probiotic can also support bone health. Clinical data is equally supportive of using L. paracasei to slow down fat accumulation and weight gain.
  • Bifidobacterium Lactis: Data from clinical trials suggests consuming B. lactis in dietary supplements may be an effective way to target stubborn belly fat.

Although Yourbiology Gut+ is not as heavily geared towards supporting weight loss as PhenQ is, it provides several probiotics that have proven to be effective for treating menopausal weight gain.

However, due to its potential in other areas, such as reducing hot flashes, YourBiology Gut+ may be a more appropriate choice for women who want a supplement that offers a broad level of support and can naturally reduce a variety of symptoms that are typical to menopause.

Yourbiology Gut+ can certainly work independently of PhenQ, but will work even better beside it and, like PhenQ, it has a 60-day money-back guarantee.

You can purchase it online from YourBiology website. The official website is available in several language options and shipping is free.

#3. Capsiplex Trim

  • Cost: $64.99 per bottle
  • Best Deal: $38.99 per bottle (buy 3 bottles get 2 free)
  • Rating: 4/5
  • Where to buy: Directly from the Capsiplex webstore

Capsiplex Trim is a powerful thermogenic fat burner pill that’s formulated especially for women. It doesn’t provide such a wide range of benefits as PhenQ and is unable to offer help with other symptoms of menopause but it’s an excellent choice for menopausal women who are prepared to put in some serious gym time and are primarily looking for supplement that can help them to torch their stores of fat faster.

Many women who use this option find it particularly useful for helping them to smash through plateaus. If you were previously losing weight and now find your progress has stalled, Using Capsiplex Trim is a good way to reclaim your mo-jo.

In addition to being a powerful fat-burning supplement, Capsiplex Trim also delivers a notable energy boost to fight fatigue and support harder-hitting workouts. It’s also formulated to help prevent loss of muscle mass due to low-calorie dieting strategies.

Key Benefits of Capsiplex Trim

  • Increases thermogenesis and fat loss
  • Boosts energy levels
  • Controls hunger
  • Preserves muscle mass

How Capsiplex Trim Works

Thermogenic fat burners produce a slight increase in body temperature. They do this by increasing a natural process called thermogenesis.  When thermogenesis increases, the body loses extra energy as heat. This enhances the calorie deficit caused by existing efforts with dieting, resulting in faster fat oxidation and weight loss.

Capsiplex Trim Ingredient Highlights

Some of the most important ingredients in Capsiplex Trim include:

  • Capsimax: Although PhenQ also contains this ingredient, Capsiplex provides it in a higher dose because its formula places greater focus on accelerated metabolism and faster fat loss. The presence of such a high dose of capsicum also furnishes Capsiplex with notable abilities as an appetite suppressant.
  • Caffeine: This is another ingredient that’s also a key component of PhenQ’s formula and, again, Capsiplex provides it in a higher dose. Although the dose is not over the top, it’s high enough to deliver very respectable improvements in workout capacity.
  • B Vitamins: B vitamins are good for enhancing energy metabolism. This makes them perfect partners for caffeine.
  • Arginine: This amino acid has been shown to simulate increases in human growth hormone (HGH) secretion. By increasing levels of this important anabolic hormone, Capsiplex Trim helps maintain or increase existing muscle mass, helping to prevent metabolism from slowing.
  • Iodine: The thyroid gland uses this mineral to produce important metabolism-regulating hormones. Iodine deficiency is more common in women than men and has the potential to slow metabolism, resulting in weight gain. 

These and the other ingredients in formula, furnish Trim with excellent credentials as a fat burner. PhenQ is the better weight management pill overall but Trim may be a more suitable choice for menopausal women who are more active than most. In common with the previous two options Capsiplex Trim has a 60-day money-back guarantee.

Best Dietary Supplements for Menopause Weight Gain – Concluding Thoughts

This article provides information about three supplements that can offer tremendous value to women struggling to reverse menopause weight gain, an aspect of menopause that I have found to be often overlooked.

Due to its ability to cover all the bases, I consider PhenQ to be the best option for most women. Although it’s not specifically designed to work as a menopause supplement, it does work as a menopause supplement for women who need to ditch the extra fat they have accumulated due to declining estrogen levels and menopause. It may work especially well when paired with Yourbiology Gut+, a dietary supplement that provides probiotic bacteria that are effective for controlling a wide range of menopause symptoms including hot flashes and reductions in bone density.

However, the probiotics in Yourbiology Gut+ can be useful for managing weight when the supplement is used solo. The only difference is the improvements in body composition may not happen so fast.

I’m primarily recommending Capsiplex Trim for women who have a keen interest in strength training and going to the gym. Especially those who have trained hard for years and always been happy with their physiques until menopause caused them to suddenly develop body fat issues.

Trim’s ability to significantly boost metabolism, should help level the playing field, while its energy-boosting capabilities support better quality workouts.

With dietary supplements, it’s seldom a case of one size fits all.



Who can use supplements for menopause weight gain?

Most women should be able to use supplements to manage symptoms of menopause, including weight gain. However, I advise women who have existing health issues such as diabetes, high blood pressure, or issues with cardiovascular health to consult a healthcare professional before using any type of dietary supplement. This is equally important where supplements will need to be used alongside prescription medications.

What are the symptoms of menopause?

Menopause can involve a variety of symptoms other than weight gain. Examples include hot flashes, night sweats, poor sleep quality, mood changes, fatigue, and poor concentration. Menopause can also affect bone mineral density, leading to weak bones and osteoporosis.

How do I get the best results from weight loss supplements?

Dietary supplements work best when paired with appropriate lifestyle factors, such as a healthy diet, regular exercise, and adequate sleep. Unhealthy habits such as smoking or overconsumption of alcohol are best avoided.

How do the best menopause supplements compare to HRT?

Although hormone replacement therapy offers obvious benefits, including potentially supporting menopause weight loss, the treatment can cause side effects and has risks many women find unacceptable. That’s why so many women choose to use natural remedies and supplements instead.

Natural supplements can work well for weight loss and other menopause symptoms and the top options do not have any known side effects. They are also cheaper.

However, if you are presently standing at a crossroads and wondering which route to take, I suggest you discuss your concerns with a healthcare provider.

What are the best supplements for weight gain during menopause?

The most effective over the counter diet pills for menopause weight gain are brands that aid weight loss on several angles. The two OTC weight loss pill brands that have a great reputation and success rate are PhenQ and YourBiology Gut+


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